New game prices almost never vary from their MSRP in North America or Japan (and when they do, it's usually not more than $5), I don't know how it works in Europe. Retailers just don't know what the official price is going to be for any of these games yet so they're using placeholders. As much as I'd like to play Star Fox 64 on a handheld, unless they're making massive additions to the game it's crazy to charge full price for it (and they will).
And yeah, it will be way more expensive in Europe, all games are.
Region locking for both cartridges and downloads was confirmed back when the system was announced. If you mean my complaint about Nintendo not bringing games to the US, I'm still waiting on Captain Rainbow, New Play Control Chibi Robo, the new DS Chibi Robo, Trace Memory 2, Disaster: Day of Crisis, Fatal Frame 4, Lost Window (I want this more than any of the others, Hotel Dusk ruled and I'm furious that we never got the sequel), and probably a few others. Those are the ones off the top of my head that I'm really disappointed we didn't get. The Last Story doesn't have a US confirmation yet either, and it's shaping up to be a really big release. Nintendo of America has been absolutely garbage this generation.
At least I can import Lost Story from Europe now that it's out in English. Won't be able to do that on the next system.
Super Walrus Land: Mouth Words Edition